Study: Ibuprofen use may be linked to male infertility - NBC12 - WWBT - Richmond, VA News On Your Side

Study: Ibuprofen use may be linked to male infertility

(Source: Wikimedia Commons) (Source: Wikimedia Commons)
(WWBT) -

A recent study shows that ibuprofen taken by young men may be linked to reduced fertility. 

"The study shows that ibuprofen use results in selective transcriptional repression of endocrine cells in the human testis," said a study published Monday in the journal Proceedings of the National Academy of Sciences. "This repression results in the elevation of the stimulatory pituitary hormones, resulting in a state of compensated hypogonadism, a disorder associated with adverse reproductive and physical health disorders."

The research team used 31 men between 18 and 35 for the study. Of that group, 14 were given a daily dosage of 600 milligrams of ibuprofen twice a day. The others were given a placebo.

Within 14 days, researchers discovered that the men who took ibuprofen experienced a 23 percent increase in levels of a hormone that's secreted by the pituitary gland and stimulates the production of testosterone.

The men's testosterone levels, however, didn't change, which leads to the condition of compensated hypogonadism. 

Compensated hypogonadism is reversible when ibuprofen is taken in a short period of time, Bernard Jégou, a co-author at French National Institute of Health and Medical Research, told CNN. That includes the study's subjects, he said. 

Jégou, however, was not sure if taking ibuprofen regularly over a longer period of time can be reversed.

The study did not examine sperm production, so researchers say additional studies are necessary. 

Copyright 2018 WWBT NBC12. All rights reserved.

Report an Error or Submit a Tip to NBC12

  • Latest news from NBC12.comNEWSMore>>

  • The Latest: Prince fan says superstar didn't get justice

    The Latest: Prince fan says superstar didn't get justice

    Thursday, April 19 2018 11:12 AM EDT2018-04-19 15:12:44 GMT
    Thursday, April 19 2018 5:23 PM EDT2018-04-19 21:23:45 GMT
    (AP Photo/Chris O'Meara, File). FILE - In this Feb. 4, 2007 file photo, Prince performs during halftime of the Super Bowl XLI football game in Miami. Minnesota prosecutors are planning an announcement Thursday, April 19, 2018, in their two-year investi...(AP Photo/Chris O'Meara, File). FILE - In this Feb. 4, 2007 file photo, Prince performs during halftime of the Super Bowl XLI football game in Miami. Minnesota prosecutors are planning an announcement Thursday, April 19, 2018, in their two-year investi...
    A Minnesota doctor accused of illegally prescribing an opioid for Prince a week before the musician died has agreed to pay $30,000 to settle a federal civil claim.More >>
    A Minnesota doctor accused of illegally prescribing an opioid for Prince a week before the musician died has agreed to pay $30,000 to settle a federal civil claim.More >>
  • Emporia native, NASCAR star throws out first pitch at Squirrels' peanut-free game

    Emporia native, NASCAR star throws out first pitch at Squirrels' peanut-free game

    Thursday, April 19 2018 5:00 PM EDT2018-04-19 21:00:27 GMT
    Elliott Sadler throws out first pitch at the Flying Squirrels game Thursday (Source: NBC12)Elliott Sadler throws out first pitch at the Flying Squirrels game Thursday (Source: NBC12)
    Elliott Sadler throws out first pitch at the Flying Squirrels game Thursday (Source: NBC12)Elliott Sadler throws out first pitch at the Flying Squirrels game Thursday (Source: NBC12)

    Emporia native and NASCAR star Elliott Sadler was at The Diamond Thursday instead of the race track to help raise awareness about a personal issue. 

    More >>

    Emporia native and NASCAR star Elliott Sadler was at The Diamond Thursday instead of the race track to help raise awareness about a personal issue. 

    More >>
  • Man charged with robbing bank, Dollar General less than a week apart

    Man charged with robbing bank, Dollar General less than a week apart

    Thursday, April 19 2018 4:58 PM EDT2018-04-19 20:58:21 GMT

    Shaveek Pittman, 22, is charged with robbery and attempted robbery in incidents less than a week apart as well as being served on outstanding warrants.

    More >>

    Shaveek Pittman, 22, is charged with robbery and attempted robbery in incidents less than a week apart as well as being served on outstanding warrants.

    More >>
Powered by Frankly